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1

DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis

Sugako Oka, Yusaku Nakabeppu

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 598 KB

english, 2011

2

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

Oka, Sugako, Ohno, Mizuki, Tsuchimoto, Daisuke, Sakumi, Kunihiko, Furuichi, Masato, Nakabeppu, Yusaku

Journal:

The EMBO Journal

Année:

2008

Langue:

english

Fichier:

PDF, 664 KB

english, 2008

3

DNA Polymerases as Potential Therapeutic Targets for Cancers Deficient in the DNA Mismatch Repair Proteins MSH2 or MLH1

Sarah A. Martin, Nuala McCabe, Michelle Mullarkey, Robert Cummins, Darren J. Burgess, Yusaku Nakabeppu, Sugako Oka, Elaine Kay, Christopher J. Lord, Alan Ashworth

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2010

4

Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death

Junji Ichikawa, Daisuke Tsuchimoto, Sugako Oka, Mizuki Ohno, Masato Furuichi, Kunihiko Sakumi, Yusaku Nakabeppu

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2008

5

Prominent bifid T waves observed in the QT prolongation caused by complete atrioventricular blockade in a hypokalemic diabetic patient

Sugako Oka-Manabe, Toru Maruyama, Ryuji Urae, Toshiaki Amamoto, Yoshiyuki Niho

Journal:

Journal of Electrocardiology

Année:

1999

Langue:

english

Fichier:

PDF, 310 KB

english, 1999

6

MutT Homolog-1 Attenuates Oxidative DNA Damage and Delays Photoreceptor Cell Death in Inherited Retinal Degeneration

Yusuke Murakami, Yasuhiro Ikeda, Noriko Yoshida, Shoji Notomi, Toshio Hisatomi, Sugako Oka, Gabriele De Luca, Yoshikazu Yonemitsu, Margherita Bignami, Yusaku Nakabeppu, Tatsuro Ishibashi

Journal:

The American Journal of Pathology

Année:

2012

Fichier:

PDF, 270 KB

2012

7

Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase

Yusaku Nakabeppu, Sugako Oka, Zijing Sheng, Daisuke Tsuchimoto, Kunihiko Sakumi

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2010

Langue:

english

Fichier:

PDF, 446 KB

english, 2010

8

Appointments.

Akimoto, Yoriko, Oka, Sugako, Leon, Julio, Nakabeppu, Yusaku

Journal:

Année:

1888

Langue:

english

Fichier:

PDF, 193 KB

english, 1888

9

Quantitative detection of oxidative DNA damage in brains of the triple transgenic Alzheimer's disease mouse model

Akimoto, Yoriko, Oka, Sugako, Leon, Julio, Nakabeppu, Yusaku

Journal:

Alzheimer's & Dementia

Année:

2013

Langue:

english

Fichier:

PDF, 232 KB

english, 2013

10

Expression of human mitochondrial transcriptional factor A (hTFAM) improves cognitive function in Alzheimer's disease model mice

Oka, Sugako, Kang, Dongchon, Nakabeppu, Yusaku

Journal:

Alzheimer's & Dementia

Année:

2013

Langue:

english

Fichier:

PDF, 49 KB

english, 2013

11

Inhibitory Effects of Dietary Spirulina platensis on UVB-Induced Skin Inflammatory Responses and Carcinogenesis

Yogianti, Flandiana, Kunisada, Makoto, Nakano, Eiji, Ono, Ryusuke, Sakumi, Kunihiko, Oka, Sugako, Nakabeppu, Yusaku, Nishigori, Chikako

Journal:

The Journal of Investigative Dermatology

Année:

2014

Langue:

english

Fichier:

PDF, 2.51 MB

english, 2014

12

Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain

Abolhassani, Nona, Leon, Julio, Sheng, Zijing, Oka, Sugako, Hamasaki, Hideomi, Iwaki, Toru, Nakabeppu, Yusaku

Journal:

Mechanisms of Ageing and Development

Année:

2016

Langue:

english

Fichier:

PDF, 616 KB

english, 2016

13

A Case of Acute Myocardial Infarction Due to Primary Coronary Dissection

Oka, Sugako, Manabe, Kazunori, Gondo, Hideyuki, Hiramatsu, Yoshihiro, Kagiyama, Yutaka, Gotou, Ikuro

Journal:

Japanese Circulation Journal

Année:

1997

Fichier:

PDF, 754 KB

1997

14

Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer’s disease

Oka, Sugako, Leon, Julio, Sakumi, Kunihiko, Ide, Tomomi, Kang, Dongchon, LaFerla, Frank M., Nakabeppu, Yusaku

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 3.57 MB

english, 2016

15

8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions

Leon, Julio, Sakumi, Kunihiko, Castillo, Erika, Sheng, Zijing, Oka, Sugako, Nakabeppu, Yusaku

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 2.35 MB

english, 2016

16

Co-regulation of Cxcl1 and versican in the inflammatory response to UVB induced reactive oxygen species in skin photo-tumorigenesis

Takemori, Chihiro, Kunisada, Makoto, Yogianti, Flandiana, Oka, Sugako, Sakumi, Kunihiko, Ono, Ryusuke, Nakabeppu, Yusaku, Nishigori, Chikako

Journal:

Journal of Dermatological Science

Année:

2017

Langue:

english

Fichier:

PDF, 909 KB

english, 2017

17

Erratum: Corrigendum: 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions

Leon, Julio, Sakumi, Kunihiko, Castillo, Erika, Sheng, Zijing, Oka, Sugako, Nakabeppu, Yusaku

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 186 KB

english, 2016

18

Co-regulation of Cxcl1 and versican in inflammatory response in UVB induced reactive oxygen species in the skin

Takemori, Chihiro, Kunisada, Makoto, Yogianti, Flandiana, Oka, Sugako, Sakumi, Kunihiko, Ono, Ryusuke, Nakabeppu, Yusaku, Nishigori, Chikako

Journal:

Journal of Dermatological Science

Année:

2017

Langue:

english

Fichier:

PDF, 50 KB

english, 2017

19

Role of the DNA repair glycosylase OGG1 in the activation of murine splenocytes

Seifermann, Marco, Ulges, Alexander, Bopp, Tobias, Melcea, Svetlana, Schäfer, Andrea, Oka, Sugako, Nakabeppu, Yusaku, Klungland, Arne, Niehrs, Christof, Epe, Bernd

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 665 KB

english, 2017

20

ROS control in human iPS cells reveals early events in spontaneous carcinogenesis

Oka, Sugako, Hayashi, Michio, Taguchi, Kenichi, Hidaka, Masumi, Tsuzuki, Teruhisa, Sekiguchi, Mutsuo

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 589 KB

english, 2019

21

8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair

Sheng, Zijing, Oka, Sugako, Tsuchimoto, Daisuke, Abolhassani, Nona, Nomaru, Hiroko, Sakumi, Kunihiko, Yamada, Hidetaka, Nakabeppu, Yusaku

Journal:

Journal of Clinical Investigation

Année:

2012

Fichier:

PDF, 13.76 MB

2012